Logical Analysis Report

Key Focus

• I would be much more comfortable with SARS data."
  Petrovsky said that while RNA vaccines are very fast to make, evidence that they are going to work is scant.
  "In the past, we've seen they have poor immunogenicity, which means they don't stimulate the immune system very well," he said.
  Said Zaks: "We've demonstrated the utility to generate the right kind of immune response time and again in multiple phase one trials."
  The challenge of a dangerous phenomenon
  One frequent hurdle for vaccine developers is a phenomenon known as disease enhancement, in which the vaccine actually promotes the infection and makes the disease worse.
  "The worst possible thing you do is vaccinate somebody to prevent infection and actually make them worse," Fauci said at a White House briefing last month.
  This phenomenon underscores the importance of animal trials, experts say.
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals he vaccinated wound up sicker than the ones he didn't vaccinate, once they were exposed to the virus.
  He told Reuters that he believes the Moderna trial should conduct animal studies prior to injecting the vaccine in humans.
  "If there is immune enhancement in laboratory animals vaccinated with the Moderna vaccine, that's a showstopper," he told the news organization.
  A Moderna spokesperson said the company has not seen signs of enhanced disease in animal trials with the MERS vaccine that it was developing with NIH.
  "Enhanced disease is a clinical finding that is very rarely seen," she said in an email.
  Potential setbacks fall into two broad categories: the vaccine isn't strong enough to produce an immune response or the vaccine causes safety issues.
  "It's possible there's no actual production of antibodies, in which because either the mRNA didn't get into the cells, the cells didn't make the proteins from the mRNA or the immune system didn't recognize those proteins
• Indeed, it took just 42 days, as Bancel told Trump.
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've done previously has essentially driven us into what we call a rapid response," said Dr. Kizzmekia Corbett, the lead scientist for coronavirus research at the National Institutes of Health, in a recent interview with CNN's Anderson Cooper and Dr. "The really interesting part about this is that we have a collaboration with Moderna," she added.
  The National Institute of Allergy and Infectious Diseases -- a branch of the NIH -- said Moderna's vaccine platform is well-suited for responding to emerging outbreaks such as novel coronaviruses.
  It "can be produced more quickly than with many other vaccine platforms," the NIAID said in an emailed statement
• If the FDA's evaluation of these data support initiating human studies of a candidate coronavirus vaccine without first completing additional toxicology studies, then the FDA would consider allowing such human studies to proceed."
  Petrovsky also noted that while NIH and Moderna worked on a MERS vaccine, they hadn't collaborated on a SARS (Severe Acute Respiratory Syndrome) vaccine

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Knowledge Graph(Read more)

Complex Event Analysis(Read more)

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High Level Topics

MODERNA

VACCINE

BANCEL

SCIENCE

High Level Abstractions

MODERNA(32, 0 Order)

( MODERNA )(32, 0 Order)  top

( MODERNA, VACCINE )(20, 1st Order)  top

( MODERNA, VACCINE, CORONAVIRUS )(7, 2nd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, IMMUNE )(2, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, FDA )(2, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, PRODUCT )(1, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, NIH )(3, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, FUNDING )(3, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, VACCINATE )(1, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, RACE )(1, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, POLITICAL )(2, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, NATIONAL_INSTITUTES )(1, 3rd Order)  top

( MODERNA, VACCINE, CORONAVIRUS, MRNA )(1, 3rd Order)  top

( MODERNA, VACCINE, IMMUNE )(3, 2nd Order)  top

( MODERNA, VACCINE, FDA )(6, 2nd Order)  top

( MODERNA, VACCINE, FDA, PRODUCT )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, ZAKS )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, WASHINGTON )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, UNPROVEN )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, TRUMP )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, SARS-COV-2 )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, SAFETY )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, ON_MONDAY )(1, 3rd Order)  top

( MODERNA, VACCINE, FDA, NINE )(1, 3rd Order)  top

( MODERNA, VACCINE, MRNA )(4, 2nd Order)  top

( MODERNA, VACCINE, EXPERTS )(5, 2nd Order)  top

( MODERNA, VACCINE, EXPERTS, IMMUNE )(1, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, AGENCY )(2, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, MRNA )(2, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, INFECTION )(1, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, ENHANCEMENT )(1, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, DISMISSAL )(1, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, ZAKS )(2, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, WHITE_HOUSE )(1, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, VIRUS )(2, 3rd Order)  top

( MODERNA, VACCINE, EXPERTS, VACCINES )(1, 3rd Order)  top

( MODERNA, VACCINE, AGENCY )(3, 2nd Order)  top

( MODERNA, VACCINE, VACCINES )(5, 2nd Order)  top

( MODERNA, VACCINE, VACCINES, IMMUNE )(2, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, MRNA )(3, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, JOHNSON )(1, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, VACCINATE )(1, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, INFECTION )(2, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, HOUSEHOLD )(2, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, FEDERAL )(2, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, ENHANCEMENT )(1, 3rd Order)  top

( MODERNA, VACCINE, VACCINES, WHITE_HOUSE )(1, 3rd Order)  top

( MODERNA, VACCINE, RACE )(2, 2nd Order)  top

( MODERNA, VACCINE, NIH )(3, 2nd Order)  top

( MODERNA, VACCINE, JOHNSON )(1, 2nd Order)  top

( MODERNA, VACCINE, FUNDING )(4, 2nd Order)  top

( MODERNA, BANCEL )(10, 1st Order)  top

( MODERNA, BANCEL, SCIENCE )(3, 2nd Order)  top

( MODERNA, BANCEL, VACCINE )(4, 2nd Order)  top

( MODERNA, BANCEL, CEO )(2, 2nd Order)  top

( MODERNA, BANCEL, INVESTORS )(3, 2nd Order)  top

( MODERNA, BANCEL, HEALTH )(2, 2nd Order)  top

( MODERNA, BANCEL, CORONAVIRUS )(1, 2nd Order)  top

( MODERNA, BANCEL, TECHNOLOGY )(2, 2nd Order)  top

( MODERNA, BANCEL, ROSSI )(1, 2nd Order)  top

( MODERNA, BANCEL, NIH )(1, 2nd Order)  top

( MODERNA, BANCEL, NATIONAL_INSTITUTES )(1, 2nd Order)  top

( MODERNA, BANCEL, MRNA )(2, 2nd Order)  top

( MODERNA, CORONAVIRUS )(8, 1st Order)  top

( MODERNA, CORONAVIRUS, IMMUNE )(2, 2nd Order)  top

( MODERNA, CORONAVIRUS, FDA )(2, 2nd Order)  top

( MODERNA, CORONAVIRUS, PRODUCT )(1, 2nd Order)  top

( MODERNA, CORONAVIRUS, NIH )(3, 2nd Order)  top

( MODERNA, CORONAVIRUS, FUNDING )(3, 2nd Order)  top

( MODERNA, CORONAVIRUS, COVID-19 )(3, 2nd Order)  top

( MODERNA, CORONAVIRUS, VACCINATE )(1, 2nd Order)  top

( MODERNA, CORONAVIRUS, RACE )(1, 2nd Order)  top

( MODERNA, CORONAVIRUS, POLITICAL )(2, 2nd Order)  top

( MODERNA, CORONAVIRUS, NATIONAL_INSTITUTES )(1, 2nd Order)  top

( MODERNA, SCIENCE )(9, 1st Order)  top

( MODERNA, SCIENCE, VACCINE )(4, 2nd Order)  top

( MODERNA, SCIENCE, EMPLOYEES )(4, 2nd Order)  top

( MODERNA, SCIENCE, DISMISSAL )(2, 2nd Order)  top

( MODERNA, SCIENCE, CORPORATE )(1, 2nd Order)  top

( MODERNA, SCIENCE, CEO )(2, 2nd Order)  top

( MODERNA, SCIENCE, AGENCY )(1, 2nd Order)  top

( MODERNA, SCIENCE, WORKFORCE )(1, 2nd Order)  top

( MODERNA, SCIENCE, VIRUS )(1, 2nd Order)  top

( MODERNA, SCIENCE, VENTURE )(2, 2nd Order)  top

( MODERNA, SCIENCE, UNIVERSITY )(1, 2nd Order)  top

( MODERNA, IMMUNE )(3, 1st Order)  top

( MODERNA, MRNA )(5, 1st Order)  top

( MODERNA, MRNA, IMMUNE )(1, 2nd Order)  top

( MODERNA, MRNA, CORONAVIRUS )(2, 2nd Order)  top

( MODERNA, MRNA, VIRUS )(2, 2nd Order)  top

( MODERNA, MRNA, NIH )(2, 2nd Order)  top

( MODERNA, MRNA, VACCINES )(3, 2nd Order)  top

( MODERNA, MRNA, VACCINATE )(1, 2nd Order)  top

( MODERNA, MRNA, NATIONAL_INSTITUTES )(1, 2nd Order)  top

( MODERNA, MRNA, INFECTION )(1, 2nd Order)  top

( MODERNA, MRNA, HEALTH )(1, 2nd Order)  top

( MODERNA, MRNA, ENHANCEMENT )(1, 2nd Order)  top

( MODERNA, FDA )(6, 1st Order)  top

( MODERNA, FDA, PRODUCT )(1, 2nd Order)  top

( MODERNA, FDA, ZAKS )(1, 2nd Order)  top

( MODERNA, FDA, WASHINGTON )(1, 2nd Order)  top

( MODERNA, FDA, UNPROVEN )(1, 2nd Order)  top

( MODERNA, FDA, TRUMP )(1, 2nd Order)  top

( MODERNA, FDA, SARS-COV-2 )(1, 2nd Order)  top

( MODERNA, FDA, SAFETY )(1, 2nd Order)  top

( MODERNA, FDA, ON_MONDAY )(1, 2nd Order)  top

( MODERNA, FDA, NINE )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY )(6, 1st Order)  top

( MODERNA, TECHNOLOGY, ROSSI )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, UNPROVEN )(2, 2nd Order)  top

( MODERNA, TECHNOLOGY, PUSHING )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, HARVARD_MEDICAL_SCHOOL )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, WEWORK )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, VALUATION )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, STEM-CELL )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, SIGMUND_FREUD )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, SCIENTISTS )(1, 2nd Order)  top

( MODERNA, TECHNOLOGY, REVENUE )(1, 2nd Order)  top

( MODERNA, PRODUCT )(3, 1st Order)  top

( MODERNA, CEO )(4, 1st Order)  top

( MODERNA, VIRUS )(2, 1st Order)  top

( MODERNA, VACCINES )(6, 1st Order)  top

( MODERNA, VACCINES, IMMUNE )(2, 2nd Order)  top

( MODERNA, VACCINES, JOHNSON )(1, 2nd Order)  top

( MODERNA, VACCINES, VACCINATE )(1, 2nd Order)  top

( MODERNA, VACCINES, SAFETY )(2, 2nd Order)  top

( MODERNA, VACCINES, INFECTION )(2, 2nd Order)  top

( MODERNA, VACCINES, HOUSEHOLD )(2, 2nd Order)  top

( MODERNA, VACCINES, FEDERAL )(2, 2nd Order)  top

( MODERNA, VACCINES, EXPERTS )(2, 2nd Order)  top

( MODERNA, VACCINES, ENHANCEMENT )(1, 2nd Order)  top

VACCINE(29, 0 Order)

( VACCINE )(29, 0 Order)  top

( VACCINE, CORONAVIRUS )(10, 1st Order)  top

( VACCINE, CORONAVIRUS, IMMUNE )(3, 2nd Order)  top

( VACCINE, CORONAVIRUS, FDA )(2, 2nd Order)  top

( VACCINE, CORONAVIRUS, PRODUCT )(2, 2nd Order)  top

( VACCINE, CORONAVIRUS, NIH )(3, 2nd Order)  top

( VACCINE, CORONAVIRUS, NATIONAL_INSTITUTES )(1, 2nd Order)  top

( VACCINE, CORONAVIRUS, HEALTH )(2, 2nd Order)  top

( VACCINE, CORONAVIRUS, FUNDING )(3, 2nd Order)  top

( VACCINE, CORONAVIRUS, VACCINES )(4, 2nd Order)  top

( VACCINE, CORONAVIRUS, VACCINATE )(1, 2nd Order)  top

( VACCINE, CORONAVIRUS, RACE )(1, 2nd Order)  top

( VACCINE, IMMUNE )(5, 1st Order)  top

( VACCINE, IMMUNE, VACCINATE )(1, 2nd Order)  top

( VACCINE, IMMUNE, SCHRUM )(2, 2nd Order)  top

( VACCINE, IMMUNE, POLITICAL )(2, 2nd Order)  top

( VACCINE, IMMUNE, MRNA )(2, 2nd Order)  top

( VACCINE, IMMUNE, INFECTION )(2, 2nd Order)  top

( VACCINE, IMMUNE, FUNDING )(2, 2nd Order)  top

( VACCINE, IMMUNE, FORMULATION )(2, 2nd Order)  top

( VACCINE, IMMUNE, ENHANCEMENT )(1, 2nd Order)  top

( VACCINE, IMMUNE, ADJUVANTS )(3, 2nd Order)  top

( VACCINE, FDA )(6, 1st Order)  top

( VACCINE, FDA, PRODUCT )(1, 2nd Order)  top

( VACCINE, FDA, ZAKS )(1, 2nd Order)  top

( VACCINE, FDA, WASHINGTON )(1, 2nd Order)  top

( VACCINE, FDA, UNPROVEN )(1, 2nd Order)  top

( VACCINE, FDA, TRUMP )(1, 2nd Order)  top

( VACCINE, FDA, SARS-COV-2 )(1, 2nd Order)  top

( VACCINE, FDA, SAFETY )(1, 2nd Order)  top

( VACCINE, FDA, ON_MONDAY )(1, 2nd Order)  top

( VACCINE, FDA, NINE )(1, 2nd Order)  top

( VACCINE, MRNA )(6, 1st Order)  top

( VACCINE, MRNA, VACCINES )(4, 2nd Order)  top

( VACCINE, MRNA, VACCINATE )(1, 2nd Order)  top

( VACCINE, MRNA, INFECTION )(1, 2nd Order)  top

( VACCINE, MRNA, ENHANCEMENT )(1, 2nd Order)  top

( VACCINE, MRNA, WHITE_HOUSE )(1, 2nd Order)  top

( VACCINE, MRNA, VIRUS )(3, 2nd Order)  top

( VACCINE, MRNA, UNPROVEN )(1, 2nd Order)  top

( VACCINE, MRNA, TROPICAL_MEDICINE )(1, 2nd Order)  top

( VACCINE, MRNA, TECHNOLOGY )(2, 2nd Order)  top

( VACCINE, BANCEL )(6, 1st Order)  top

( VACCINE, BANCEL, CORONAVIRUS )(2, 2nd Order)  top

( VACCINE, BANCEL, WHITE_HOUSE_CORONAVIRUS_TASK_FORCE )(1, 2nd Order)  top

( VACCINE, BANCEL, WHITE_HOUSE )(1, 2nd Order)  top

( VACCINE, BANCEL, TRUMP )(2, 2nd Order)  top

( VACCINE, BANCEL, SCHLEIFER )(1, 2nd Order)  top

( VACCINE, BANCEL, NIH )(2, 2nd Order)  top

( VACCINE, BANCEL, NATIONAL_INSTITUTES )(1, 2nd Order)  top

( VACCINE, BANCEL, HEALTH )(1, 2nd Order)  top

( VACCINE, BANCEL, DONALD_TRUMP )(1, 2nd Order)  top

( VACCINE, BANCEL, CABINET_ROOM )(1, 2nd Order)  top

( VACCINE, VACCINES )(8, 1st Order)  top

( VACCINE, VACCINES, IMMUNE )(3, 2nd Order)  top

( VACCINE, VACCINES, JOHNSON )(1, 2nd Order)  top

( VACCINE, VACCINES, VACCINATE )(1, 2nd Order)  top

( VACCINE, VACCINES, INFECTION )(2, 2nd Order)  top

( VACCINE, VACCINES, HOUSEHOLD )(2, 2nd Order)  top

( VACCINE, VACCINES, FEDERAL )(2, 2nd Order)  top

( VACCINE, VACCINES, EXPERTS )(2, 2nd Order)  top

( VACCINE, VACCINES, ENHANCEMENT )(1, 2nd Order)  top

( VACCINE, TRUMP )(4, 1st Order)  top

( VACCINE, NIH )(4, 1st Order)  top

( VACCINE, EXPERTS )(5, 1st Order)  top

( VACCINE, EXPERTS, IMMUNE )(1, 2nd Order)  top

( VACCINE, EXPERTS, AGENCY )(2, 2nd Order)  top

( VACCINE, EXPERTS, VACCINATE )(1, 2nd Order)  top

( VACCINE, EXPERTS, MRNA )(2, 2nd Order)  top

( VACCINE, EXPERTS, INFECTION )(1, 2nd Order)  top

( VACCINE, EXPERTS, ENHANCEMENT )(1, 2nd Order)  top

( VACCINE, EXPERTS, DISMISSAL )(1, 2nd Order)  top

( VACCINE, EXPERTS, ZAKS )(2, 2nd Order)  top

( VACCINE, EXPERTS, WHITE_HOUSE )(1, 2nd Order)  top

( VACCINE, EXPERTS, VIRUS )(2, 2nd Order)  top

( VACCINE, AGENCY )(3, 1st Order)  top

( VACCINE, WHITE_HOUSE )(3, 1st Order)  top

BANCEL(14, 0 Order)

( BANCEL )(14, 0 Order)  top

( BANCEL, SCIENCE )(4, 1st Order)  top

( BANCEL, CEO )(3, 1st Order)  top

( BANCEL, CORONAVIRUS )(2, 1st Order)  top

( BANCEL, VIRUS )(1, 1st Order)  top

( BANCEL, TECHNOLOGY )(2, 1st Order)  top

( BANCEL, NIH )(2, 1st Order)  top

( BANCEL, INVESTORS )(3, 1st Order)  top

( BANCEL, HEALTH )(2, 1st Order)  top

( BANCEL, WHITE_HOUSE_CORONAVIRUS_TASK_FORCE )(1, 1st Order)  top

( BANCEL, WHITE_HOUSE )(1, 1st Order)  top

SCIENCE(12, 0 Order)

( SCIENCE )(12, 0 Order)  top

( SCIENCE, VACCINE )(5, 1st Order)  top

( SCIENCE, VACCINE, DISMISSAL )(1, 2nd Order)  top

( SCIENCE, VACCINE, AGENCY )(1, 2nd Order)  top

( SCIENCE, VACCINE, THERANOS )(2, 2nd Order)  top

( SCIENCE, VACCINE, EXPERTS )(3, 2nd Order)  top

( SCIENCE, VACCINE, EMPLOYEES )(2, 2nd Order)  top

( SCIENCE, VACCINE, EMPLOYEE )(1, 2nd Order)  top

( SCIENCE, VACCINE, COMPLIANCE )(1, 2nd Order)  top

( SCIENCE, EMPLOYEES )(4, 1st Order)  top

( SCIENCE, DISMISSAL )(2, 1st Order)  top

( SCIENCE, MIT )(2, 1st Order)  top

( SCIENCE, CORPORATE )(1, 1st Order)  top

( SCIENCE, CEO )(2, 1st Order)  top

( SCIENCE, AGENCY )(1, 1st Order)  top

( SCIENCE, WORKFORCE )(1, 1st Order)  top

( SCIENCE, WEWORK )(1, 1st Order)  top

( SCIENCE, VIRUS )(2, 1st Order)  top

References

• ( MODERNA )  top
• ( MODERNA, VACCINE )  top
• ( MODERNA, VACCINE, CORONAVIRUS )  top
• ( MODERNA, VACCINE, CORONAVIRUS, IMMUNE )  top
• (Read more)   top
  "In the past, we've seen they have poor immunogenicity, which means they don't stimulate the immune system very well," he said.
  Said Zaks: "We've demonstrated the utility to generate the right kind of immune response time and again in multiple phase one trials."
  The challenge...
• (Read more)   top
  Anderson added that there is a "theoretical possibility" that the vaccine could trigger an "enhanced immune response" that actually worsens the illness.
  This is what happens when coronavirus research funding gets political
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine...
• ( MODERNA, VACCINE, CORONAVIRUS, FDA )  top
• (Read more)   top
  On March 3 -- the day after the roundtable -- the FDA green-lit Moderna's product for trial, making it the first vaccine candidate to advance to the first phase of a clinical study, in which an as-yet unapproved vaccine is injected into the arms of...
• (Read more)   top"If the FDA's evaluation of these data support initiating human studies of a candidate coronavirus vaccine without first completing additional toxicology studies, then the FDA would consider allowing such human studies...
• ( MODERNA, VACCINE, CORONAVIRUS, PRODUCT )  top
• (Read more)   top
  On March 3 -- the day after the roundtable -- the FDA green-lit Moderna's product for trial, making it the first vaccine candidate to advance to the first phase of a clinical study, in which an as-yet unapproved vaccine is injected into the arms of a small group of 45 human volunteers.
  Established...
• ( MODERNA, VACCINE, CORONAVIRUS, NIH )  top
• (Read more)   top
  The National Institute of Allergy and Infectious Diseases -- a branch of the NIH -- said Moderna's vaccine platform is well-suited for responding to emerging outbreaks such as novel coronaviruses.
  It "can be produced more quickly than with many other vaccine platforms,"...
• (Read more)   top
  Petrovsky also noted that while NIH and Moderna worked on a MERS vaccine, they hadn't collaborated on a SARS (Severe Acute Respiratory Syndrome) vaccine
• (Read more)   top
  A Moderna spokesperson said the company has not seen signs of enhanced disease in animal trials with the MERS vaccine that it was developing with NIH.
  "Enhanced disease is a clinical finding that is very rarely seen," she said in an email.
  Potential setbacks fall into two broad categories: the vaccine isn't strong enough to produce an immune response...
• ( MODERNA, VACCINE, CORONAVIRUS, FUNDING )  top
• (Read more)   top
  Major funding injected into vaccine race
  The effort received another boost on April 16, when the federal Biomedical Advanced Research and Development Authority (BARDA) awarded Moderna up to $483 million to accelerate...
• (Read more)   top
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals he vaccinated...
• (Read more)   top
  This is what happens when coronavirus research funding gets political
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key...
• ( MODERNA, VACCINE, CORONAVIRUS, VACCINATE )  top
• (Read more)   top
  "The worst possible thing you do is vaccinate somebody to prevent infection and actually make them worse," Fauci said at a White House briefing last month.
  This phenomenon underscores the importance of animal trials, experts say.
  This...
• ( MODERNA, VACCINE, CORONAVIRUS, RACE )  top
• (Read more)   top With a hope-starved world cheering it on, Moderna officially burst out of the gate, marking the beginning of the race for a vaccine for the new coronavirus.
  Major funding injected into vaccine race
  The effort received another boost on April 16, when the federal Biomedical Advanced Research and Development Authority...
• ( MODERNA, VACCINE, CORONAVIRUS, POLITICAL )  top
• (Read more)   top
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals he vaccinated wound up sicker than the...
• (Read more)   top
  This is what happens when coronavirus research funding gets political
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key element to conjure a...
• ( MODERNA, VACCINE, CORONAVIRUS, NATIONAL_INSTITUTES )  top
• (Read more)   top
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've...
• ( MODERNA, VACCINE, CORONAVIRUS, MRNA )  top
• (Read more)   top
  "It's possible there's no actual production of antibodies, in which because either the mRNA didn't get into the cells, the cells didn't make the proteins from the mRNA or the immune system didn't recognize those proteins
• ( MODERNA, VACCINE, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   top
  "We have not used adjuvants in our vaccine clinical trials," the spokesperson wrote in an email, adding that the trials have shown that Moderna's vaccines induce an immune response similar to that seen with natural infection.
  Expert report predicts up to two more years of pandemic misery
  The former BARDA official told CNN that Moderna generates a lot of "hype"...
• ( MODERNA, VACCINE, FDA )  top
• ( MODERNA, VACCINE, FDA, PRODUCT )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• ( MODERNA, VACCINE, FDA, ZAKS )  top
• (Read more)   top
  But while these experts felt dosing humans before animal trials could happen was questionable in practice, Zaks of Moderna said it would be "unethical to wait," given the urgency of the pandemic.
  The FDA, in a statement to CNN, said it was "unable to comment on specific unapproved products."...
• ( MODERNA, VACCINE, FDA, WASHINGTON )  top
• (Read more)   top
  The federally funded trial for Moderna's vaccine candidate began in Washington state on March 16 -- two weeks after the roundtable.
• ( MODERNA, VACCINE, FDA, UNPROVEN )  top
• (Read more)   top"An unproven platform for a new disease with no animal testing."
  Can Trump make good on his vaccine promise.
  But while these experts felt dosing humans before animal trials could happen was questionable...
• ( MODERNA, VACCINE, FDA, TRUMP )  top
• (Read more)   top
  Can Trump make good on his vaccine promise.
  But while these experts felt dosing humans before animal trials could happen was questionable in practice, Zaks of Moderna said it would be "unethical to wait,"...
• ( MODERNA, VACCINE, FDA, SARS-COV-2 )  top
• (Read more)   top So when Chinese researchers released the genomic sequence for the new coronavirus -- SARS-CoV-2, which causes the deadly disease known as Covid-19 -- in mid-January, they had a jump start.
  On March 3 -- the day after the roundtable -- the FDA green-lit Moderna's product for trial, making...
• ( MODERNA, VACCINE, FDA, SAFETY )  top
• (Read more)   top
  Meantime, Moderna is indeed moving at a fast clip: On Monday, it submitted a proposal to the FDA to enter Phase 2, subject to final safety findings from Phase 1.
  (The second phase of a typical clinical study ramps up the number of people -- often into the hundreds, including more members of at-risk groups
• ( MODERNA, VACCINE, FDA, ON_MONDAY )  top
• (Read more)   top
  Meantime, Moderna is indeed moving at a fast clip: On Monday, it submitted a proposal to the FDA to enter Phase 2, subject to final safety findings from Phase 1.
  (The second phase of a typical clinical study ramps up the number of people -- often into the hundreds,...
• ( MODERNA, VACCINE, FDA, NINE )  top
• (Read more)   top
  Established in 2010, Moderna has never brought a product to market, or gotten any of its nine or so vaccine candidates approved for use by the FDA. It has also never brought a product to the third and final phase of a clinical trial.
  And yet at the moment, it represents one of the country's...
• ( MODERNA, VACCINE, MRNA )  top
• (Read more)   top
  But Moderna -- which has at least 15 products in clinical trials -- was the first company with an mRNA vaccine that advanced to human trials, though another German mRNA company has since entered the race and another isn't far behind
• (Read more)   top
  In a "Mad Money" interview on CNBC in January, Bancel wowed host Jim Cramer with his description of a potential therapeutic "personalized cancer vaccine" by Moderna using mRNA technology.
  "In our lifetime." Cramer asked.
  "It's happening actually right now," Bancel answered
• (Read more)   top"Once the genetic information of a given emerging virus becomes available, scientists can quickly select a sequence to express an immunogen in the existing mRNA platform."
  The science has its skeptics
  But some experts are skeptical of the science.
  For starters, in the rush to get started, the FDA allowed Moderna's RNA vaccine -- called mRNA-1273...
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , MRNA )
• ( MODERNA, VACCINE, EXPERTS )  top
• ( MODERNA, VACCINE, EXPERTS, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• ( MODERNA, VACCINE, EXPERTS, AGENCY )  top
• (Read more)   top
  Director of key vaccine agency says his dismissal was retaliation
  Director of key vaccine agency says his dismissal was retaliation 02:59
  "I think Moderna has a strong compliance culture," said the former director,...
• (Read more)   top." However, it said that when the agency evaluates the need for a vaccine study, it considers the relevant data.
• ( MODERNA, VACCINE, EXPERTS, MRNA )  top
• (Read more)   topSee ( MODERNA , VACCINE , MRNA )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , MRNA )
• ( MODERNA, VACCINE, EXPERTS, INFECTION )  top
• (Read more)   top
  One frequent hurdle for vaccine developers is a phenomenon known as disease enhancement, in which the vaccine actually promotes the infection and makes the disease worse.
  "The worst possible thing you do is vaccinate somebody to prevent infection and actually make them worse," Fauci said at a White House briefing last month.
  This...
• ( MODERNA, VACCINE, EXPERTS, ENHANCEMENT )  top
• (Read more)   top
  One frequent hurdle for vaccine developers is a phenomenon known as disease enhancement, in which the vaccine actually promotes the infection and makes the disease worse.
  "The worst possible thing you do is vaccinate somebody to prevent infection and actually make them worse,"...
• ( MODERNA, VACCINE, EXPERTS, DISMISSAL )  top
• (Read more)   top
  Director of key vaccine agency says his dismissal was retaliation
  Director of key vaccine agency says his dismissal was retaliation 02:59
  "I think Moderna has a strong compliance culture," said the former director, who spoke on condition...
• ( MODERNA, VACCINE, EXPERTS, ZAKS )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , ZAKS )
• (Read more)   top
  Said Zaks: "We've demonstrated the utility to generate the right kind of immune response time and again in multiple phase one trials."
  The challenge of a dangerous phenomenon
  One frequent hurdle...
• ( MODERNA, VACCINE, EXPERTS, WHITE_HOUSE )  top
• (Read more)   top
  "The worst possible thing you do is vaccinate somebody to prevent infection and actually make them worse," Fauci said at a White House briefing last month.
  This phenomenon underscores the importance of animal trials, experts say.
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean...
• ( MODERNA, VACCINE, EXPERTS, VIRUS )  top
• (Read more)   top"Once the genetic information of a given emerging virus becomes available, scientists can quickly select a sequence to express an immunogen in the existing mRNA platform."
  The science has its skeptics
  But some experts are skeptical of the science.
  For...
• (Read more)   top ... Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals he vaccinated wound up sicker than the ones he didn't vaccinate, once they were exposed to the virus.
  He told Reuters that he believes the Moderna trial should conduct animal studies prior to injecting the vaccine in humans.
  "If there is immune enhancement in laboratory animals vaccinated with the...
• ( MODERNA, VACCINE, EXPERTS, VACCINES )  top
• (Read more)   top
  Petrovsky said that while RNA vaccines are very fast to make, evidence that they are going to work is scant.
  "In the past, we've seen they have poor immunogenicity, which means they don't stimulate the immune system very well,"...
• ( MODERNA, VACCINE, AGENCY )  top
• (Read more)   topThat amounts to about half of what the federal agency has doled out, with Janssen Research & Development -- part of Johnson & Johnson -- receiving $456 million, and a third company, Sanofi, receiving up to $30 million.
  Johnson & Johnson is a household...
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , AGENCY )
• ( MODERNA, VACCINE, VACCINES )  top
• ( MODERNA, VACCINE, VACCINES, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   topSee ( MODERNA , VACCINE , IMMUNE )
• ( MODERNA, VACCINE, VACCINES, MRNA )  top
• (Read more)   topSee ( MODERNA , VACCINE , MRNA )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , MRNA )
• ( MODERNA, VACCINE, VACCINES, JOHNSON )  top
• (Read more)   topThat amounts to about half of what the federal agency has doled out, with Janssen Research & Development -- part of Johnson & Johnson -- receiving $456 million, and a third company, Sanofi, receiving up to $30 million.
  Johnson & Johnson is a household name with a long list of approved medicines; Sanofi has been making...
• ( MODERNA, VACCINE, VACCINES, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( MODERNA, VACCINE, VACCINES, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• (Read more)   top ... adjuvants in our vaccine clinical trials," the spokesperson wrote in an email, adding that the trials have shown that Moderna's vaccines induce an immune response similar to that seen with natural infection.
  Expert report predicts up to two more years of pandemic misery
  The former BARDA official told CNN that Moderna generates a lot of "hype" for an organization that has never entered the third and final...
• ( MODERNA, VACCINE, VACCINES, HOUSEHOLD )  top
• (Read more)   top
  Johnson & Johnson is a household name with a long list of approved medicines; Sanofi has been making vaccines for more than 100 years
• (Read more)   top
  As it happens, although Moderna is not a household name, it's a company with a storied history.
  CNN Investigates interviewed more than 20 experts and former employees for this story and found that while some of the scientists expressed optimism...
• ( MODERNA, VACCINE, VACCINES, FEDERAL )  top
• (Read more)   topThat amounts to about half of what the federal agency has doled out, with Janssen Research & Development -- part of Johnson & Johnson -- receiving $456 million, and a third company, Sanofi, receiving up to $30 million.
  Johnson & Johnson is a household...
• (Read more)   top
  Others raised concerns about the science, or challenged the wisdom of the federal government-sanctioned shortcuts in the ongoing clinical trial, in particular the FDA's approval to gloss over the animal trials that normally precede injecting an untested vaccine into healthy humans.
  Dr....
• ( MODERNA, VACCINE, VACCINES, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( MODERNA, VACCINE, VACCINES, WHITE_HOUSE )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , WHITE_HOUSE )
• ( MODERNA, VACCINE, RACE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , RACE )
• (Read more)   top
  But Moderna -- which has at least 15 products in clinical trials -- was the first company with an mRNA vaccine that advanced to human trials, though another German mRNA company has since entered the race and another isn't far behind.
• ( MODERNA, VACCINE, NIH )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( MODERNA, VACCINE, JOHNSON )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , JOHNSON )
• ( MODERNA, VACCINE, FUNDING )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FUNDING )
• (Read more)   topModerna also has been allocated the most funding by BARDA, a division of the US Department of Health and Human Services.
  BARDA said it plans to fund a variety of approaches.
  "More than one vaccine is likely to be the solution," a BARDA...
• ( MODERNA, BANCEL )  top
• ( MODERNA, BANCEL, SCIENCE )  top
• (Read more)   top
  The culture of the company seems to have stabilized: In the past five years, it has ranked as a top biopharmaceutical employer in Science magazine's Top Employers Survey.
  But there were growing pains, some of which centered on Bancel, the only CEO the company has ever had.
  Afeyan, a venture capitalist with a PhD in biochemical...
• (Read more)   top. The holder of a Master of Science in chemical engineering from the University of Minnesota and an MBA from Harvard Business School joined in 2011.
  Bancel's leadership style has come under fire from employees who have described...
• (Read more)   top
  "Ninety percent of the things in science fail -- that's the way the inventions are made," Siddiqi said.
• ( MODERNA, BANCEL, VACCINE )  top
• (Read more)   top You'll have a vaccine to go into testing."
  Oxford University is partnering with a vaccine manufacturer, trial results expected in June
  Oxford University is partnering with a vaccine manufacturer, trial results expected...
• (Read more)   topIn Phase 3, the vaccine is given to thousands of people and tested for efficacy and safety, according to the Centers for Disease Control and Prevention.)
  Over the years, Moderna has sold investors on the revolutionary potential...
• (Read more)   top
  In a "Mad Money" interview on CNBC in January, Bancel wowed host Jim Cramer with his description of a potential therapeutic "personalized cancer vaccine" by Moderna using mRNA technology.
  "In our lifetime." Cramer asked.
  "It's happening actually right now," Bancel answered
• (Read more)   top
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've done previously has essentially driven us into what we call a rapid...
• ( MODERNA, BANCEL, CEO )  top
• (Read more)   top
  But there were growing pains, some of which centered on Bancel, the only CEO the company has ever had.
  Afeyan, a venture capitalist with a PhD in biochemical engineering from MIT, had tried to recruit Bancel to lead other projects, but Bancel -- formerly the CEO of a French...
• (Read more)   top
  But Rossi, who later went on to become an associate professor at Harvard Medical School and is now the CEO of another biotech company called Convelo Therapeutics, said he believes in the technology.
• ( MODERNA, BANCEL, INVESTORS )  top
• (Read more)   top
  Over the years, Moderna has sold investors on the revolutionary potential of its medicine. Bancel has been the chief narrator of the company's intoxicating story.
  "We feel this is most probably the only time in our lives that we will...
• (Read more)   top
  Rossi said he butted heads with Bancel, and that the company and its investors had a way of taking credit for the ideas of its scientists, including his own -- an allegation that Moderna's leadership denies.
  But Rossi, who later went on to become an associate professor at...
• (Read more)   top"The CEO's job is to make money for investors."
  Afeyan, the Moderna board chairman, fiercely defends Bancel. He told CNN the characterizations of Bancel as a gifted fundraiser are misplaced and even "derogatory," saying it's a way for detractors...
• ( MODERNA, BANCEL, HEALTH )  top
• (Read more)   top... which around-the-clock hours were the norm and failed experiments -- a fact of life in the world of science -- could be met with reprimand or even dismissal, according to a 2016 investigation by Stat, a health publication.
  The former executive, who left in 2016, recalled that Bancel seemed to have two versions of himself: the calm public persona who makes speeches and appears on TED Talks, and the private...
• (Read more)   top
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've done previously...
• ( MODERNA, BANCEL, CORONAVIRUS )  top
• (Read more)   top
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've done previously has essentially driven us into what we call...
• ( MODERNA, BANCEL, TECHNOLOGY )  top
• (Read more)   top
  But in 2014, the work environment became too much even for Rossi, a co-founder of Moderna, who says his team developed the company's core technology at Harvard Medical School.
  Rossi said he butted heads with Bancel, and that the company and its investors had a way of taking credit for the ideas of its scientists, including his own -- an allegation...
• (Read more)   top
  In a "Mad Money" interview on CNBC in January, Bancel wowed host Jim Cramer with his description of a potential therapeutic "personalized cancer vaccine" by Moderna using mRNA technology.
  "In our lifetime." Cramer asked.
  "It's happening actually right now," Bancel answered
• ( MODERNA, BANCEL, ROSSI )  top
• (Read more)   top
  But in 2014, the work environment became too much even for Rossi, a co-founder of Moderna, who says his team developed the company's core technology at Harvard Medical School.
  Rossi said he butted heads with Bancel, and that the company and its investors had...
• ( MODERNA, BANCEL, NIH )  top
• (Read more)   top
  Largely because of the ongoing cooperation between Moderna and NIH, the process of designing the mRNA for delivery was lightning fast. Indeed, it took just 42 days, as Bancel told Trump.
  Officials with the National Institutes of Health are bullish.
  Lead scientist...
• ( MODERNA, BANCEL, NATIONAL_INSTITUTES )  top
• (Read more)   top
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've...
• ( MODERNA, BANCEL, MRNA )  top
• (Read more)   topSee ( MODERNA , VACCINE , MRNA )
• (Read more)   top
  Largely because of the ongoing cooperation between Moderna and NIH, the process of designing the mRNA for delivery was lightning fast. Indeed, it took just 42 days, as Bancel told Trump.
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could...
• ( MODERNA, CORONAVIRUS )  top
• ( MODERNA, CORONAVIRUS, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• ( MODERNA, CORONAVIRUS, FDA )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FDA )
• ( MODERNA, CORONAVIRUS, PRODUCT )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• ( MODERNA, CORONAVIRUS, NIH )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( MODERNA, CORONAVIRUS, FUNDING )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FUNDING )
• ( MODERNA, CORONAVIRUS, COVID-19 )  top
• (Read more)   top So when Chinese researchers released the genomic sequence for the new coronavirus -- SARS-CoV-2, which causes the deadly disease known as Covid-19 -- in mid-January, they had a jump start.
  On March 3 -- the day after the roundtable -- the FDA green-lit Moderna's product for trial, making it the first vaccine candidate to advance to the first...
• (Read more)   top
  Then came the new coronavirus and Covid-19, which has killed nearly 63,000 Americans since February and 233,000 people worldwide.
  For the world, it was a disaster
• (Read more)   top
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key element to conjure a strong efficacy in any vaccine: the adjuvants.
  Adjuvants stimulate the body's immune system to react to the vaccine antigen -- the molecules...
• ( MODERNA, CORONAVIRUS, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( MODERNA, CORONAVIRUS, RACE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , RACE )
• ( MODERNA, CORONAVIRUS, POLITICAL )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , POLITICAL )
• ( MODERNA, CORONAVIRUS, NATIONAL_INSTITUTES )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NATIONAL_INSTITUTES )
• ( MODERNA, SCIENCE )  top
• ( MODERNA, SCIENCE, VACCINE )  top
• (Read more)   top But much of Moderna's appeal is not what it has done, but what it says is possible: to develop a vaccine -- which normally takes years -- in record speed.
  As it happens, although Moderna is not a household name, it's a company with a storied history.
  CNN Investigates interviewed more than...
• (Read more)   top
  Hear what it's like to be part of a vaccine trial
  Hear what it's like to be part of a vaccine trial 04:04
  "Deals don't validate science," the op-ed said
• (Read more)   top
  Director of key vaccine agency says his dismissal was retaliation
  Director of key vaccine agency says his dismissal was retaliation 02:59
  "I think Moderna has a strong compliance culture," said the former...
• (Read more)   top
  For starters, in the rush to get started, the FDA allowed Moderna's RNA vaccine -- called mRNA-1273 -- to essentially gloss over the animal-testing that typically precede clinical trials in humans
• ( MODERNA, SCIENCE, EMPLOYEES )  top
• (Read more)   top
  CNN Investigates interviewed more than 20 experts and former employees for this story and found that while some of the scientists expressed optimism that Moderna can pull it off, others voiced criticism about the hype the company has generated over the years, as well as...
• (Read more)   top
  In any case, the company has published dozens of papers in recent years, and several experts and former Moderna employees contacted by CNN for this story rejected any comparison to Theranos, saying the science is sound.
  One former employee, who worked at the company for three years ending in 2019 -- most recently as...
• (Read more)   topOver the span of a decade, the size of its workforce has expanded from four employees to more than 700.
  The culture of the company seems to have stabilized: In the past five years, it has ranked as a top biopharmaceutical employer in Science magazine's Top Employers Survey.
  But...
• (Read more)   top
  Bancel's leadership style has come under fire from employees who have described a pressure-cooker atmosphere in which around-the-clock hours were the norm and failed experiments -- a fact of life in the world of science -- could be met with reprimand or even dismissal,...
• ( MODERNA, SCIENCE, DISMISSAL )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , DISMISSAL )
• (Read more)   top... employees who have described a pressure-cooker atmosphere in which around-the-clock hours were the norm and failed experiments -- a fact of life in the world of science -- could be met with reprimand or even dismissal, according to a 2016 investigation by Stat, a health publication.
  The former executive, who left in 2016, recalled that Bancel seemed to have two versions of himself: the calm public persona who...
• ( MODERNA, SCIENCE, CORPORATE )  top
• (Read more)   top
  The former executive, who left in 2016, recalled that Bancel seemed to have two versions of himself: the calm public persona who makes speeches and appears on TED Talks, and the private version in corporate meetings.
  "What you hear in corporate meetings is stuff like this, 'What the f**k are you taking about
• ( MODERNA, SCIENCE, CEO )  top
• (Read more)   top ... similar to that of Theranos, now disgraced for raising some $700 million in venture capital for a blood-testing technology that turned out to be a sham, turning the now-dissolved company and its embattled CEO into a symbol of tech hubris run amok.
  Hear what it's like to be part of a vaccine trial
  Hear what it's like to be part of a vaccine trial 04:04
  "Deals don't validate science,"...
• (Read more)   topSee ( MODERNA , BANCEL , CEO )
• ( MODERNA, SCIENCE, AGENCY )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , AGENCY )
• ( MODERNA, SCIENCE, WORKFORCE )  top
• (Read more)   topOver the span of a decade, the size of its workforce has expanded from four employees to more than 700.
  The culture of the company seems to have stabilized: In the past five years, it has ranked as a top biopharmaceutical employer in Science magazine's...
• ( MODERNA, SCIENCE, VIRUS )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VIRUS )
• ( MODERNA, SCIENCE, VENTURE )  top
• (Read more)   top
  But Moderna's unbridled ambition, reputation for secrecy and preoccupation with venture capital have earned it detractors.
  In 2016, an op-ed published in the science journal Nature scolded Moderna for not having published a single peer-reviewed paper outlining the science of its dazzling...
• (Read more)   top
  Afeyan, a venture capitalist with a PhD in biochemical engineering from MIT, had tried to recruit Bancel to lead other projects, but Bancel -- formerly the CEO of a French diagnostics company -- had turned him down.
  "I...
• ( MODERNA, SCIENCE, UNIVERSITY )  top
• (Read more)   top. The holder of a Master of Science in chemical engineering from the University of Minnesota and an MBA from Harvard Business School joined in 2011.
  Bancel's leadership style has come under fire from employees who have described a pressure-cooker atmosphere in which around-the-clock...
• ( MODERNA, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   topSee ( MODERNA , VACCINE , IMMUNE )
• ( MODERNA, MRNA )  top
• ( MODERNA, MRNA, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• ( MODERNA, MRNA, CORONAVIRUS )  top
• (Read more)   topSee ( MODERNA , BANCEL , CORONAVIRUS )
• (Read more)   top
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals...
• ( MODERNA, MRNA, VIRUS )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VIRUS )
• ( MODERNA, MRNA, NIH )  top
• (Read more)   topSee ( MODERNA , BANCEL , NIH )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( MODERNA, MRNA, VACCINES )  top
• (Read more)   top
  To be sure, a handful of other vaccine candidates have since entered the human trial phase, and more than 80 companies and academic labs are working on vaccines to add to the mix.
  But Moderna -- which has at least 15 products in clinical trials -- was the first company with an mRNA vaccine that advanced to human trials, though another German mRNA company...
• (Read more)   topBecause people said, 'Oh, vaccines, nobody's going to pay for that -- it's no big deal.'"
  But Bancel -- who pulled in a salary of more than $920,000, plus a bonus of $1 million in 2019 -- has ably applied his persuasive...
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VACCINES )
• ( MODERNA, MRNA, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( MODERNA, MRNA, NATIONAL_INSTITUTES )  top
• (Read more)   topSee ( MODERNA , BANCEL , NATIONAL_INSTITUTES )
• ( MODERNA, MRNA, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• ( MODERNA, MRNA, HEALTH )  top
• (Read more)   topSee ( MODERNA , BANCEL , HEALTH )
• ( MODERNA, MRNA, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( MODERNA, FDA )  top
• ( MODERNA, FDA, PRODUCT )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• ( MODERNA, FDA, ZAKS )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , ZAKS )
• ( MODERNA, FDA, WASHINGTON )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , WASHINGTON )
• ( MODERNA, FDA, UNPROVEN )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , UNPROVEN )
• ( MODERNA, FDA, TRUMP )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , TRUMP )
• ( MODERNA, FDA, SARS-COV-2 )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , SARS-COV-2 )
• ( MODERNA, FDA, SAFETY )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , SAFETY )
• ( MODERNA, FDA, ON_MONDAY )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , ON_MONDAY )
• ( MODERNA, FDA, NINE )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , NINE )
• ( MODERNA, TECHNOLOGY )  top
• ( MODERNA, TECHNOLOGY, ROSSI )  top
• (Read more)   topSee ( MODERNA , BANCEL , ROSSI )
• ( MODERNA, TECHNOLOGY, UNPROVEN )  top
• (Read more)   top
  Moderna's unproven but potentially paradigm-shattering technology has garnered enthusiastic press: Moderna was ranked No. 1 on the CNBC Disrupter 50 list in 2015 for its goal to help "the human body make the medicine...
• (Read more)   topRaising some $600 million, its initial public offering was the largest in the history of biotech -- despite the fact that its technology remained unproven.
  Moderna's valuation ballooned to $7.5 billion -- up from an already impressive $5 billion from a year and a half prior.
  Still, there were signs of an impending nosedive: Moderna -- which currently generates...
• ( MODERNA, TECHNOLOGY, PUSHING )  top
• (Read more)   top It is his personality -- that he's pushing hard and he expected everybody's pushing the same way."
  The former director who left in 2019 said Bancel has brought in a leadership team with experience in biopharmaceutical development that...
• ( MODERNA, TECHNOLOGY, HARVARD_MEDICAL_SCHOOL )  top
• (Read more)   top
  But in 2014, the work environment became too much even for Rossi, a co-founder of Moderna, who says his team developed the company's core technology at Harvard Medical School.
  Rossi said he butted heads with Bancel, and that the company and its investors had a way of taking credit for the ideas of its scientists, including his own -- an allegation that Moderna's leadership denies.
  But...
• ( MODERNA, TECHNOLOGY, WEWORK )  top
• (Read more)   top ... 1 on the CNBC Disrupter 50 list in 2015 for its goal to help "the human body make the medicine it needs to cure a disease," putting it in company with eventually the likes of Airbnb, Lyft and WeWork.
• ( MODERNA, TECHNOLOGY, VALUATION )  top
• (Read more)   top
  Moderna's valuation ballooned to $7.5 billion -- up from an already impressive $5 billion from a year and a half prior.
  Still, there were signs of an impending nosedive: Moderna -- which currently generates revenue...
• ( MODERNA, TECHNOLOGY, STEM-CELL )  top
• (Read more)   top Rossi, once an associate professor at Harvard, was hailed by Time magazine as one of the 100 most influential people of 2011 for a novel stem-cell treatment; Langer of MIT is ranked by Google as the eighth most-cited researcher in the world, just a few notches below Sigmund Freud.
  Moderna's unproven but potentially paradigm-shattering technology...
• ( MODERNA, TECHNOLOGY, SIGMUND_FREUD )  top
• (Read more)   top ... magazine as one of the 100 most influential people of 2011 for a novel stem-cell treatment; Langer of MIT is ranked by Google as the eighth most-cited researcher in the world, just a few notches below Sigmund Freud.
  Moderna's unproven but potentially paradigm-shattering technology has garnered enthusiastic press: Moderna was ranked No. 1 on the CNBC Disrupter 50 list in 2015 for its goal to help "the human body make...
• ( MODERNA, TECHNOLOGY, SCIENTISTS )  top
• (Read more)   top
  Rossi said he butted heads with Bancel, and that the company and its investors had a way of taking credit for the ideas of its scientists, including his own -- an allegation that Moderna's leadership denies.
  But Rossi, who later went on to become an associate professor at Harvard Medical School and is now the CEO of another biotech...
• ( MODERNA, TECHNOLOGY, REVENUE )  top
• (Read more)   top
  Still, there were signs of an impending nosedive: Moderna -- which currently generates revenue primarily through investments by collaboration partners -- ended 2019 with a $514 million net loss
• ( MODERNA, PRODUCT )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• (Read more)   top
  In 2016, an op-ed published in the science journal Nature scolded Moderna for not having published a single peer-reviewed paper outlining the science of its dazzling product, even as it participated in a "schmoozefest" at a JP Morgan healthcare conference in San Francisco that announced $350 million in investments.
  The piece noted that Moderna's then lack of...
• (Read more)   top
  "He's a skilled team builder, he's a skilled product developer, he's a skilled strategist, he's a skilled partnership forger.
• ( MODERNA, CEO )  top
• (Read more)   topSee ( MODERNA , SCIENCE , CEO )
• (Read more)   topSee ( MODERNA , BANCEL , CEO )
• (Read more)   top
  But Zaks says Moderna has delivered on its promises to US officials about its coronavirus vaccine, saying, "When our CEO said that we would get this fast into the clinic, we did."
  That, he said, combined with the company's potential, is why "the US government stepped in and picked our platform as one of...
• ( MODERNA, VIRUS )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VIRUS )
• ( MODERNA, VACCINES )  top
• ( MODERNA, VACCINES, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   topSee ( MODERNA , VACCINE , IMMUNE )
• ( MODERNA, VACCINES, JOHNSON )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , JOHNSON )
• ( MODERNA, VACCINES, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( MODERNA, VACCINES, SAFETY )  top
• (Read more)   topMessenger RNA activates the body's instinct to get rid of the foreign invader, which works better for single dose vaccines but creates safety issues for longer-term use in chronic diseases.
  Jeff Ellsworth, who served as Moderna's former senior director of preclinical pharmacology and the head of rare genetic diseases until he left in...
• (Read more)   top
  Potential setbacks fall into two broad categories: the vaccine isn't strong enough to produce an immune response or the vaccine causes safety issues.
  "It's possible there's no actual production of antibodies, in which because either the mRNA didn't get into the cells, the cells didn't make the proteins from the mRNA...
• ( MODERNA, VACCINES, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , INFECTION )
• ( MODERNA, VACCINES, HOUSEHOLD )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , HOUSEHOLD )
• ( MODERNA, VACCINES, FEDERAL )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , FEDERAL )
• ( MODERNA, VACCINES, EXPERTS )  top
• (Read more)   top
  CNN Investigates interviewed more than 20 experts and former employees for this story and found that while some of the scientists expressed optimism that Moderna can pull it off, others voiced criticism about the hype the company has generated over...
• (Read more)   top
  This phenomenon underscores the importance of animal trials, experts say.
  This is what happens when coronavirus research funding gets political
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development...
• ( MODERNA, VACCINES, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( VACCINE )  top
• ( VACCINE, CORONAVIRUS )  top
• ( VACCINE, CORONAVIRUS, IMMUNE )  top
• (Read more)   top
  Conventional vaccines involve injecting a tiny piece of a weakened or dead virus into the body to stimulate an immune response in the cells.
  In theory, an mRNA vaccine enables scientists to plug a small piece of the coronavirus's genetic code into a human cell to create a synthetic copy of the virus's spike...
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• ( VACCINE, CORONAVIRUS, FDA )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FDA )
• ( VACCINE, CORONAVIRUS, PRODUCT )  top
• (Read more)   top
  One by one, vaccine developers at a White House roundtable convened by President Donald Trump in early March pitched their product as a viable solution to the coronavirus that was spreading globally and killing Americans.
  John Shiver, the head of R&D for Sanofi Pasteur vaccines, said he could have a product ready for the clinic...
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• ( VACCINE, CORONAVIRUS, NIH )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( VACCINE, CORONAVIRUS, NATIONAL_INSTITUTES )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NATIONAL_INSTITUTES )
• ( VACCINE, CORONAVIRUS, HEALTH )  top
• (Read more)   top Its scientists had already been collaborating with researchers from the National Institutes of Health on a vaccine for another coronavirus, Middle Eastern Respiratory Syndrome (MERS). So when Chinese researchers released the genomic sequence for the new coronavirus -- SARS-CoV-2, which causes the deadly...
• (Read more)   top
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot of our work that we've done previously...
• ( VACCINE, CORONAVIRUS, FUNDING )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FUNDING )
• ( VACCINE, CORONAVIRUS, VACCINES )  top
• (Read more)   top
  John Shiver, the head of R&D for Sanofi Pasteur vaccines, said he could have a product ready for the clinic in a year -- perhaps a vaccine for the public in as "few as several years."
  Trump seemed uninterested.
  "Right
• (Read more)   top
  Dr. Myron Levine, a professor and infectious disease expert at the University of Maryland School of Medicine, cautioned that most vaccines fail.
  "I've been in this business a very long time -- a half a century," he said
• (Read more)   top
  Conventional vaccines involve injecting a tiny piece of a weakened or dead virus into the body to stimulate an immune response in the cells.
  In theory, an mRNA vaccine enables scientists to plug a small piece of the coronavirus's...
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VACCINES )
• ( VACCINE, CORONAVIRUS, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( VACCINE, CORONAVIRUS, RACE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , RACE )
• ( VACCINE, IMMUNE )  top
• ( VACCINE, IMMUNE, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( VACCINE, IMMUNE, SCHRUM )  top
• (Read more)   top
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key element to conjure a strong efficacy...
• (Read more)   top
  "Typically, what you see in any vaccine if they use adjuvants, they clearly identify that and say this is the purpose of using in the vaccine formulation as an adjuvant," said Schrum, who is no longer with the company.
• ( VACCINE, IMMUNE, POLITICAL )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , POLITICAL )
• ( VACCINE, IMMUNE, MRNA )  top
• (Read more)   top
  Moderna didn't invent the mRNA approach, but is the company that has "cornered the market" on the idea, said the former executive who left in 2016.
  "Henry Ford wasn't the first carmaker, but he managed to scale...
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , MRNA )
• ( VACCINE, IMMUNE, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , INFECTION )
• ( VACCINE, IMMUNE, FUNDING )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , FUNDING )
• ( VACCINE, IMMUNE, FORMULATION )  top
• (Read more)   top
  Jason Schrum, a founding scientist at Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key element to conjure a strong efficacy in any vaccine: the adjuvants.
  Adjuvants stimulate the body's immune...
• (Read more)   top
  "Typically, what you see in any vaccine if they use adjuvants, they clearly identify that and say this is the purpose of using in the vaccine formulation as an adjuvant," said Schrum, who is no longer with the company.
• ( VACCINE, IMMUNE, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( VACCINE, IMMUNE, ADJUVANTS )  top
• (Read more)   top ... Moderna, also pointed out that the vaccine formulation listed on Moderna's clinical trial page for Covid-19 doesn't seem to include a key element to conjure a strong efficacy in any vaccine: the adjuvants.
  Adjuvants stimulate the body's immune system to react to the vaccine antigen -- the molecules that trigger an immune response in the body
• (Read more)   top
  "Typically, what you see in any vaccine if they use adjuvants, they clearly identify that and say this is the purpose of using in the vaccine formulation as an adjuvant," said Schrum, who is no longer with the company
• (Read more)   top
  "We have not used adjuvants in our vaccine clinical trials," the spokesperson wrote in an email, adding that the trials have shown that Moderna's vaccines induce an immune response similar to that seen with natural infection.
  Expert...
• ( VACCINE, FDA )  top
• ( VACCINE, FDA, PRODUCT )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , PRODUCT )
• ( VACCINE, FDA, ZAKS )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , ZAKS )
• ( VACCINE, FDA, WASHINGTON )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , WASHINGTON )
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• (Read more)   topSee ( MODERNA , VACCINE , FDA , UNPROVEN )
• ( VACCINE, FDA, TRUMP )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , TRUMP )
• ( VACCINE, FDA, SARS-COV-2 )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , SARS-COV-2 )
• ( VACCINE, FDA, SAFETY )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , SAFETY )
• ( VACCINE, FDA, ON_MONDAY )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , ON_MONDAY )
• ( VACCINE, FDA, NINE )  top
• (Read more)   topSee ( MODERNA , VACCINE , FDA , NINE )
• ( VACCINE, MRNA )  top
• ( VACCINE, MRNA, VACCINES )  top
• (Read more)   topSee ( MODERNA , MRNA , VACCINES )
• (Read more)   topSee ( VACCINE , CORONAVIRUS , VACCINES )
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VACCINES )
• ( VACCINE, MRNA, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( VACCINE, MRNA, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• ( VACCINE, MRNA, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( VACCINE, MRNA, WHITE_HOUSE )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , WHITE_HOUSE )
• ( VACCINE, MRNA, VIRUS )  top
• (Read more)   top
  Conventional vaccines involve injecting a tiny piece of a weakened or dead virus into the body to stimulate an immune response in the cells.
  In theory, an mRNA vaccine enables scientists to plug a small piece of the coronavirus's genetic code into a human cell to create a...
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , VIRUS )
• ( VACCINE, MRNA, UNPROVEN )  top
• (Read more)   top ... Flinders University in Australia, who is collaborating with Oracle to use computer models and AI technology to develop a Covid-19 vaccine, has concerns about the mRNA trials, insisting the US government has taken an unproven vaccine and "put (it) straight into humans."
  "It's a double game," he said
• ( VACCINE, MRNA, TROPICAL_MEDICINE )  top
• (Read more)   top
  Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, worked on development of a vaccine for SARS. Some of the animals he vaccinated wound up sicker than the ones he didn't vaccinate, once they were exposed to the...
• ( VACCINE, MRNA, TECHNOLOGY )  top
• (Read more)   topSee ( MODERNA , BANCEL , TECHNOLOGY )
• (Read more)   top
  Professor Nikolai Petrovsky at Flinders University in Australia, who is collaborating with Oracle to use computer models and AI technology to develop a Covid-19 vaccine, has concerns about the mRNA trials, insisting the US government has taken an unproven vaccine and "put (it) straight into humans."
  "It's a double game,"...
• ( VACCINE, BANCEL )  top
• ( VACCINE, BANCEL, CORONAVIRUS )  top
• (Read more)   top
  The new coronavirus, according to Forbes, turned the 47-year-old Bancel into a billionaire.
  Vaccine pipeline is a funnel: 'very few things survive'
  To try to bring a vaccine to market is to try to beat the...
• (Read more)   topSee ( MODERNA , BANCEL , CORONAVIRUS )
• ( VACCINE, BANCEL, WHITE_HOUSE_CORONAVIRUS_TASK_FORCE )  top
• (Read more)   top
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in...
• ( VACCINE, BANCEL, WHITE_HOUSE )  top
• (Read more)   top
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  Stephane Bancel of...
• ( VACCINE, BANCEL, TRUMP )  top
• (Read more)   top"With phase two," Bancel clarified, just before Fauci interjected, for Trump's benefit: "You won't have a vaccine.
• (Read more)   top Indeed, it took just 42 days, as Bancel told Trump.
  Officials with the National Institutes of Health are bullish.
  Lead scientist says coronavirus vaccine could be ready soon
  Lead scientist says coronavirus vaccine could be ready soon 01:35
  "A lot...
• ( VACCINE, BANCEL, SCHLEIFER )  top
• (Read more)   top He leaned over the table and interrupted Schleifer mid-pitch.
  "So that process would be faster than John's." he said, pointing at Shiver.
  "It would be," Schleifer said, adding that the process could take "weeks to months."
  The...
• ( VACCINE, BANCEL, NIH )  top
• (Read more)   top ... Dr. Anthony Fauci, and said he is "very proud to be working with the US government and to have already sent, in only 42 days from the sequence of the virus, our vaccine to Dr. Fauci's team at the NIH."
  The French-born Bancel went on to say that he needed just "a few months" to start phase two of a three-part clinical trial of the sort that typifies vaccine development
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( VACCINE, BANCEL, NATIONAL_INSTITUTES )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NATIONAL_INSTITUTES )
• ( VACCINE, BANCEL, HEALTH )  top
• (Read more)   topSee ( VACCINE , CORONAVIRUS , HEALTH )
• ( VACCINE, BANCEL, DONALD_TRUMP )  top
• (Read more)   top
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  President Donald Trump leads a meeting with the White House Coronavirus Task Force...
• ( VACCINE, BANCEL, CABINET_ROOM )  top
• (Read more)   top
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  Stephane...
• ( VACCINE, VACCINES )  top
• ( VACCINE, VACCINES, IMMUNE )  top
• (Read more)   topSee ( VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• (Read more)   topSee ( MODERNA , VACCINE , IMMUNE )
• ( VACCINE, VACCINES, JOHNSON )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , JOHNSON )
• ( VACCINE, VACCINES, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( VACCINE, VACCINES, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , INFECTION )
• ( VACCINE, VACCINES, HOUSEHOLD )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , HOUSEHOLD )
• ( VACCINE, VACCINES, FEDERAL )  top
• (Read more)   topSee ( MODERNA , VACCINE , VACCINES , FEDERAL )
• ( VACCINE, VACCINES, EXPERTS )  top
• (Read more)   topSee ( MODERNA , VACCINES , EXPERTS )
• ( VACCINE, VACCINES, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( VACCINE, TRUMP )  top
• (Read more)   top
  This got Trump's attention.
• (Read more)   top"With phase two," Bancel clarified, just before Fauci interjected, for Trump's benefit: "You won't have a vaccine. You'll have a vaccine to go into testing."
  Oxford University is partnering with a vaccine manufacturer, trial results expected in June
  Oxford University...
• (Read more)   topSee ( VACCINE , BANCEL , TRUMP )
• (Read more)   topSee ( MODERNA , VACCINE , FDA , TRUMP )
• ( VACCINE, NIH )  top
• (Read more)   topSee ( VACCINE , BANCEL , NIH )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , NIH )
• ( VACCINE, EXPERTS )  top
• ( VACCINE, EXPERTS, IMMUNE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , IMMUNE )
• ( VACCINE, EXPERTS, AGENCY )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , AGENCY )
• ( VACCINE, EXPERTS, VACCINATE )  top
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , VACCINATE )
• ( VACCINE, EXPERTS, MRNA )  top
• (Read more)   topSee ( MODERNA , VACCINE , MRNA )
• (Read more)   topSee ( MODERNA , VACCINE , CORONAVIRUS , MRNA )
• ( VACCINE, EXPERTS, INFECTION )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , INFECTION )
• ( VACCINE, EXPERTS, ENHANCEMENT )  top
• (Read more)   topSee ( MODERNA , VACCINE , EXPERTS , ENHANCEMENT )
• ( VACCINE, EXPERTS, DISMISSAL )  top
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  One by one, vaccine developers at a White House roundtable convened by President Donald Trump in early March pitched their product as a viable solution to the coronavirus that was spreading globally and killing Americans.
  John Shiver, the head...
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• (Read more)   top ... complicated and many things fail," Bancel, who declined CNN an interview, responded in a written statement. "I don't recall one employee being fired since we started the company, because of science failing.
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  The only way to top that was to start talking about days, and it's exactly what the next CEO did.
  President Donald Trump leads a meeting with the White House Coronavirus Task Force and pharmaceutical executives in the Cabinet Room of the White House on March 2.
  President Donald Trump leads...
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• (Read more)   top ... nation's top infectious disease expert, Dr. Anthony Fauci, and said he is "very proud to be working with the US government and to have already sent, in only 42 days from the sequence of the virus, our vaccine to Dr. Fauci's team at the NIH."
  The French-born Bancel went on to say that he needed just "a few months" to start phase two of a three-part clinical trial of the...
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  The piece noted that Moderna's then lack of scientific publishing was similar to that of Theranos, now disgraced for raising some $700 million in venture capital for a blood-testing technology that turned out to be a sham, turning the now-dissolved company and its embattled CEO into a symbol of tech...
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  In any case, the company has published dozens of papers in recent years, and several experts and former Moderna employees contacted by CNN for this story rejected any comparison to Theranos, saying the science is sound.
  One former employee, who worked at the company for three years ending in 2019 -- most recently as a director -- called the comparison "absurd."
  Director of...
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  In any case, the company has published dozens of papers in recent years, and several experts and former Moderna employees contacted by CNN for this story rejected any comparison to Theranos, saying the science is sound.
  One former employee, who worked at the company for three years ending...
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  But some experts are skeptical of the science.
  For starters, in the rush to get started, the FDA allowed Moderna's RNA vaccine -- called mRNA-1273 -- to essentially gloss over the animal-testing that typically...
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  One former employee, who worked at the company for three years ending in 2019 -- most recently as a director -- called the comparison "absurd."
  Director of key vaccine agency says his dismissal was retaliation
  Director...
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  "I think Moderna has a strong compliance culture," said the former director, who spoke on condition of anonymity, saying the biotech industry is a small world and he didn't feel comfortable making a public statement
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• (Read more)   top Rossi, once an associate professor at Harvard, was hailed by Time magazine as one of the 100 most influential people of 2011 for a novel stem-cell treatment; Langer of MIT is ranked by Google as the eighth most-cited researcher in the world, just a few notches below Sigmund Freud.
  Moderna's unproven but potentially paradigm-shattering technology has garnered enthusiastic...
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  Afeyan, a venture capitalist with a PhD in biochemical engineering from MIT, had tried to recruit Bancel to lead other projects, but Bancel -- formerly the CEO of a French diagnostics company -- had turned him down.
  "I told him I was willing to take a career risk by working...
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