Complex Event Analysis - Report

Complex Event Analysis - REPORT

Supporting narratives:

• challenge (Read more)
• Others suffer severe symptoms, fighting to breathe on a ventilator for weeks, if they survive at all.
  Despite a concerted global scientific effort, doctors still lack a clear picture of why this is.
  Could genetic differences explain the differences we see in symptoms and severity of COVID-19.
  To test this, we used computer models to analyze known genetic variation within the human immune system.
• High Level Abstractions:
• (computer,coronavirus)
• (coronavirus,immune)
• Inferred entity relationships (3)

  (coronavirus,immune,moderna,vaccine) [inferred]

  (coronavirus,immune,moderna) [inferred]

  (coronavirus,immune,vaccine) [inferred]

• challenge (Read more)
• ET
  By Austin Nguyen, Abhinav Nellore and Reid Thompson
  Differences in HLA genes may be a significant reason for huge differences in infections
  When some people become infected with the coronavirus, they only develop mild or undetectable cases of COVID-19. Others suffer severe symptoms, fighting to breathe on a ventilator for weeks, if they survive at all.
  Despite a concerted global scientific effort, doctors still lack a clear picture of why this is.
  Could genetic differences explain the differences we see in symptoms and severity of COVID-19.
  To test this, we used computer models to analyze known genetic variation within the human immune system
• High Level Abstractions:
• (coronavirus,undetectable)
• (coronavirus,covid-19)
• Inferred entity relationships (1)

  (coronavirus,covid-19,moderna) [inferred]

• WIP (Read more)
• Abhinav Nellore is an assistant professor of biomedical engineering and surgery and Reid Thompson is an assistant professor of radiation medicine, both also at Oregon Health & Science University
• High Level Abstractions:
• (biomedical,coronavirus)
• (coronavirus,reid_thompson)

• WIP (Read more)
• In theory, we could repeat this analysis to better understand the genetic risks of many viruses that currently or could potentially infect humans.
  Now read:Treating a typical coronavirus infection is four times the cost of a case of the flu
  Austin Nguyen is a Ph.D. candidate in computational biology and biomedical engineering at Oregon Health & Science University in Portland.
• High Level Abstractions:
• (coronavirus,oregon_health)
• (biomedical,coronavirus)

• WIP (Read more)
• Abhinav Nellore is an assistant professor of biomedical engineering and surgery and Reid Thompson is an assistant professor of radiation medicine, both also at Oregon Health & Science University. This was first published by The Conversation. "Your genes could determine whether the coronavirus puts you in the hospital - and we're starting to unravel which ones matter"
• High Level Abstractions:
• (coronavirus,oregon_health)

• WIP (Read more)
• and some of these alleles are more sensitive to certain viruses or pathogens than others.
  To test whether different alleles of this alarm system could explain some of the range in immune responses to SARS-CoV-2, we first retrieved a list of all the proteins that make up the coronavirus from an online database.
  We then took that list and used existing computer algorithms to predict how well different versions of the anti-viral alarm system detected these coronavirus proteins.
  A model of an HLA protein (green and yellow) bound to a piece of a virus (orange and blue) - in this case, influenza
• High Level Abstractions:
• (coronavirus,sars-cov-2)
• (coronavirus,hla)
• (computer,coronavirus)
• (alleles,coronavirus)
• (coronavirus,immune)
• (coronavirus,virus)
• Inferred entity relationships (3)

  (coronavirus,immune,moderna,vaccine) [inferred]

  (coronavirus,immune,moderna) [inferred]

  (coronavirus,immune,vaccine) [inferred]

Target rule match count: 15.0 Challenge: 0.20 Momentum: 0.00 WIP: 0.30